Ciaran Sualdam O'Brien, MD

Awards and Honors

Penn Center of Surgical Excellence Award, 2024

William Y. Inouye Resident Award, 2021

Alpha Omega Alpha Medical Honor Society

Selected Publications

Biagetti G, Thompson E, O'Brien C, Damrauer S. The Role of Genetics in Managing Peripheral Arterial Disease. Ann Vasc Surg. 2024 Nov;108:279-286. doi: 10.1016/j.avsg.2024.04.022. Epub 2024 Jul 2. PMID: 38960093."

Concors SJ, Hernandez PT, O'Brien C, DePaolo J, Murken DR, Aufhauser DD, Wang Z, Xiong Y, Krumeich L, Ge G, Beier UH, Bhatti TR, Kozikowski AP, Avelar LAA, Kurz T, Hancock WW, Levine MH. Differential Effects of HDAC6 Inhibition Versus Knockout During Hepatic Ischemia-Reperfusion Injury Highlight Importance of HDAC6 C-terminal Zinc-finger Ubiquitin-binding Domain. Transplantation. 2024 Oct 1;108(10):2084-2092. doi: 10.1097/TP.0000000000005042. Epub 2024 Sep 24. PMID: 38685198."

Hernandez P, O'Brien C, Concors SJ, Wang Z, Ge G, Hancock WW, Levine MH. The Selective Estrogen Receptor Modulator, Raloxifene, Is Protective Against Renal Ischemia-reperfusion Injury. Transplantation. 2022 Nov 1;106(11):2166-2171. doi: 10.1097/TP.0000000000004194. Epub 2022 Oct 21. PMID: 35655356; PMCID: PMC12063156."

Aufhauser DD Jr, Hernandez P, Concors SJ, O'Brien C, Wang Z, Murken DR, Samanta A, Beier UH, Krumeich L, Bhatti TR, Wang Y, Ge G, Wang L, Cheraghlou S, Wagner FF, Holson EB, Kalin JH, Cole PA, Hancock WW, Levine MH. HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury. Sci Rep. 2021 Apr 27;11(1):9018. doi: 10.1038/s41598-021-88242-3. PMID: 33907245; PMCID: PMC8079686."

O'Brien C, Monteagudo J, Schad C, Cheung E, Middlesworth W. Centrifugal pumps and hemolysis in pediatric extracorporeal membrane oxygenation (ECMO) patients: An analysis of Extracorporeal Life Support Organization (ELSO) registry data. J Pediatr Surg. 2017 Jun;52(6):975-978. doi: 10.1016/j.jpedsurg.2017.03.022. Epub 2017 Mar 16. PMID: 28359588."

Dutia R, Embrey M, O'Brien CS, Haeusler RA, Agénor KK, Homel P, McGinty J, Vincent RP, Alaghband-Zadeh J, Staels B, le Roux CW, Yu J, Laferrère B. Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes. Int J Obes (Lond). 2015 May;39(5):806-13. doi: 10.1038/ijo.2015.1. Epub 2015 Jan 20. Erratum in: Int J Obes (Lond). 2016 Mar;40(3):554. doi: 10.1038/ijo.2015.250.. O'Brien, S [corrected to O'Brien, C S]. PMID: 25599611; PMCID: PMC4422767.